Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
It is estimated that over 89m enterprise retirees and more than 17m institution retirees will benefit from the adjustment.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
3所在这份榜单上叱咤多年的重量级学府——哈佛商学院(HBS)、伦敦商学院(LBS)和麻省理工斯隆管理学院(MIT Sloan School of Management)的排名下滑。哈佛商学院的排名下降两个位次，今年排在第四，这是这所位于波士顿的学府9年来首次跌出前三甲。伦敦商学院下滑3个位次，排在第六，为14年来最低。麻省理工斯隆管理学院的排名下滑至第13位，为10年来首次跌出前10。
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
It organized two large-scale inspections last year, involving more than 5,300 batches of imported consumer goods, such as air purifiers, car brake blocks, household electrical appliances and clothes, with more than 1,500 found to be substandard, Han said.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Here are our top 10expectations for China in 2014:
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
In terms of the volume of exports from emerging markets, Mr Baweja would not rule out growth of around 4-5 per cent. But while this would represent a modest improvement on recent years, growth at this rate would still be “in the bottom quartile over the long-term distribution, even maybe the second decile”, given that median growth has been about 7 per cent a year over the past 25 years.
It has been speculated by varying sources that with MGM back up and running, Sony Entertainment, the company that distributed the last two 007 adventures Casino Royale and Quantum of Solace, will announce their take over of the franchise. Deadline, on the other hand, tend to believe that James Bond 23 may go to Paramount, as they have a very close relationship with Spyglass and are currently working with them to produce Star Trek 2.
Trends and targets in antiviral phototherapy
She is now so successful that her mother has hired a security team who monitor the star 24/7.
Regulators clamped down on outbound deals following an unprecedented flood of offshore acquisitions in 2016 that drained China’s foreign exchange reserves. In August this year, China’s cabinet formalised a new framework that encourages deals that fit Beijing’s strategic priorities and discourages deals in entertainment, sports and luxury real estate
‘Jeopardy!’ This game show celebrated the 50th anniversary of its debut (broadcast on March 30, 1964), and proved it can still not only stump viewers but also surprise them. That’s not just because the host, Alex Trebek, briefly regrew a mustache after 13 clean-shaven years, but also because some contestants showed they could still rile an audience. This year, it was Arthur Chu, who introduced a blitzkrieg style of gamesmanship that provoked a cyber hate-fest. His strategy was thrilling and certainly effective: he came in second in the Tournament of Champions. (Ben Ingram, the nice guy, finished first.)
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Costco CEO Craig Jelinek
Newly launched Eleven James is bringing collaborative consumption to men’s watches. With a membership program offering access to a curated collection of high-end watches, Eleven James is extending the membership model that has previously been associated with private jets, luxury cars and vacation homes. Beyond the watches, members are enrolled in a dedicated loyalty program which includes a concierge service, access to partner benefits and unique experiences like watch-themed events. Sounds a little bit like men’s watches meet a Net Jets experience? Founder Randy Brandoff has deep experience in luxury marketing, having previously served as the Senior Vice President and Chief Marketing Officer of Net Jets and the Executive Vice President and Chief Marketing Officer of Marquis Jets. Combining his expertise with a watch industry that’s grown year over year and a business model that’s proven successful in other markets, it looks like Eleven James could be hitting the market at just the right time.
ACE2 as a potential therapeutic target for pandemic COVID-19
Stevens会演唱电影《以你的名字呼唤我》中《Mystery of Love》，以及Bernal, LaFourcade和 Miguel会合唱《寻梦环游记》中的歌曲《Remember Me》。
Diagnostic technologies for COVID-19: a review
Edgar Wright’s Baby Driver is one of the most entertaining thrill rides of this year, this decade. This century.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Female founders in Silicon Valley will raise more money next year, as sexual harassment scandals have forced investors to rethink their habit of backing ventures founded by mainly young, white men. Some start-ups founded by men pursued by rumours of unsavoury pasts will not get funding, even if they are a good investment proposition.
Effective bosses and managers tend to:
On April 24, Zhou took the pesticide to the Yimin Technician Training School in Rongchang, Chongqing and hid the toxic substance under a desk.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
It was unearthed by archaeologists in 2012 and has since been kept at the Yizheng Museum. It is not shown to the public.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
6. 《出租车》(Taxi)，导演贾法·帕纳西(Jafar Panahi)。
Singer Susan Boyle came undone -- literally, when her trousers popped open at a soccer match as she waved a Celtic fan above her head in Scotland. The "Britain
Another fashion high-flyer making her mark on the first day of the world-famous festival was Winnie Harlow. The Canadian model - who has the skin condition vitiligo - nearly took Emily's crown, as she made a play for the attention with her elegant belle of the ball outfit.
Influenza neuraminidase: A druggable target for natural products
According to the new report, over the past 20 years India has been the leading user of anti-dumping cases, filing 767, or 15 per cent, of the 4,990 initiated between 1995 and 2015. The US accounted for 570 while the EU registered 480.
11. Arctic and Antarctic sea ice volumes both fall to an all-time low
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
It is estimated that over 89m enterprise retirees and more than 17m institution retirees will benefit from the adjustment.
以丹麦为例，如今，88%的丹麦人口都是白人——这样的多数地位很难动摇。但在1980年，也就是上一代人的时候，丹麦有97%的人口是白人。反移民的丹麦人民党(Danish People’s Party)现在是丹麦议会中的第二大党。在德国，从2011年到2015年间，非本土出生人口激增了大约75%，反移民的民粹政党德国另类选择党(Alternative for Germany)如今获得了破纪录的支持率。
The role of biosensors in the detection of emerging infectious diseases
Here's a full rundown of the activity—and inactivity—with an eye towards naming this year's trade deadline winners and losers.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Online registration will end on Oct. 24. The exam will be held on Nov. 27 in major Chinese cities.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
简而言之，C型人格的人是完美主义者， 始终如一，永远不会违反规则。 与A型人格的人不同的是，C型人会花时间处理细节，经常反复检查工作是否准确。他们往往是深思熟虑的人，喜欢了解自己工作和生活的每一个细节。
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
"It's a goal that's right here and now and it's something that we want to experience," Curry said. "It'd be a huge accomplishment because doing something that hasn't been done in the history of the league is special. You never know if this opportunity will come back again. There are so many variables that go into winning this many in a row, especially the start of the season."
Bernard Baumohl 作为Economic Outlook Group的首席经济学家，表示他甚至更乐观的认为接下来的两年将会成为至少近十年以来形势最好的两年，他还称“有很多证据充分的表明了经济正在恢复的势头”。
Inhibition of SARS coronavirus helicase by bismuth complexes
A 14-year-old Chinese boy overcame two of humankind's most dreaded fears--getting stuck in an elevator and getting homework done, in a single night thanks to his quick-witted character.
As the cameras cut away to the cast and crew of "La La Land" hugging, Beatty could be heard saying something such as, "It says Emma Stone," with Dunaway replying, "What?" As the La La Land cast were walking on stage to accept the accolade, a stagehand standing in the wings could be heard saying "Oh ... Oh my god, he got the wrong envelope".
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Bernard Baumohl, chief global economist of the Economic Outlook Group, said he is even more optimistic. "The next two years could be the best two we have seen in at least a decade," he said. "There is clearly a lot of evidence the economy is gaining a lot of momentum."
When the cup is lifted and removed from the dispenser, the magnet seals the bottom and the drink is ready to be enjoyed.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
They may be in opposite corners of the globe, but Hong Kong, Sydney and Vancouver have one thing in common.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
The unprecedented declines have raised worries that the reserves could quickly evaporate if capital outflows continue and the central bank continues to defend the exchange rate. Most analysts believe the central bank will be forced to curtail its intervention in order to prevent further depletion of its reserves.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
British schools outperform the French on both new criteria. Warwick Business School, the top UK school for career progress, is second overall for the criterion, 30 places above the first French school, HEC Paris. Alumni from UK schools also see a higher increase between their first salary after graduation and now, at 62 per cent versus 45 per cent. However, UK school alumni still have a lower salary on average than their counterparts who studied in France, at $55,000 versus $64,000.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Opening song “Usher In The Spring With Beautiful Melodies” (48 CCTV hosts and hostesses)
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
adj. 在 ... 之前，先，前，以前的
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Domestic brands still dominate cellphone shipments in China as Chinese cellphone makers accelerated innovation, an industrial report showed.
Finance and real estate made up the backbone of home-grown brands, with 38 and 23 companies coming into the list respectively, and accounting for 30 percent of the brands on the list.
Musical theatre actors, Callabro united to become a truly talented vocal group who have gone from strength to strength.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
The fastest-rising sector is apparel, driven by Nike in sportswear as people pay more attention to health and fitness, and Zara, whose fast fashion is becoming increasingly popular in China.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Next year, crude from Libya--which experienced major problems exporting its oil in 2013 because of internal disputes--could flow again. Iraqi output also is set to increase. Even Iran, shut out of global markets for years, could return if an agreement is reached to relax sanctions aimed at curbing its nuclear development. All this could add as much as two million to three million barrels a day of Middle East output.
Believe it or not, this prize went to the US Government General Accountability Office (GAO) for issuing a report that recommended a report about another report of reports recommending reports... or something like that.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Judge Business School at Cambridge University in the UK was the biggest riser, climbing 19 places to 29th thanks to a strong performance in the executive MBA ranking in its first participation in that list. Warwick Business School made a comeback to the top 20 (19) after missing out on the MiM ranking in 2013.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
The US has overtaken India as the leading user of anti-dumping and other trade defence cases, with China and its steel sector the biggest target, according to research.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
3.Sit in the Front Row
报告指出，中国网游开发商自今年年初以来一直在考虑按照时间收费。在排名前十的网络游戏中，时间收费型网游占据了4个席位，其中两款是今年才开始商业化运营的新游戏，包括盛大互动娱乐有限公司(Shanda Interactive Entertainment)的主要新游戏《永恒之塔》(AION)。Cnzz.com说，转向时间收费模式更有可能给游戏带来公平和公正感，因为玩的最好的玩家将是那些花时间最多的人，而不是那些花钱最多的用户。
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Comic skit “Dance If You Like” (Cai Ming and Pan Changjiang)
'I just want to stay professional. I don't want them to think I'm a fangirl. I'm one of the performers and I'm not just a background dancer, I'm the dancer.'
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Subdivided flats smaller than 100 square feet (9 square meters) can rent for $385 in the Asian city.
A modular microarray imaging system for highly specific COVID-19 antibody testing
No.1: Einstein Alive Again?
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
伦敦商学院(London Business School，见上图)荣登2014年英国《金融时报》欧洲商学院排行榜榜首，该学院上一次夺得冠军宝座是在2005年。法国巴黎高等商学院(HEC Paris)和西班牙企业商学院(IE Business School)分列二、三位。
The rest of the top 10 2016 highest-paid actresses are:
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Cross-cultural Instrumental performance (Yanni, USA, and Chang Jing)
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
1.Under no circumstances should you ask your taxi driver how excited he is about having the Olympics in London this summer. It's not that he will be reluctant or embarrassed to offer a personal opinion on the matter. That is not the problem at all.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
斯坦福大学的Zhenan Baohas 研发出了一种具备超弹性、超耐性和超敏感的材料，能够作为未来发展人工皮肤的基础。以前，人们也研究过生化皮肤，但是Baohas的材料比以前研发出来的更具敏感性。它带有有机转换物质和一层弹性材料，保证它在不被破坏情况下的延展性。另外，这种材料带有一系列的太阳能电池元件，可以自动充电。
The swap is due largely to the major security breach at software company Adobe in October which affected tens of millions of users.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Loyal employees of this auto services company are rewarded on their 10th anniversary -- and every five years after --with a weekend getaway at a resort in Boca Raton, Fla. (The company is headquartered just 15 minutes away.)
Pushing ahead with the five priority tasks through reform
A facile assay for rapid detection of COVID-19 antibodies
Jinan took the first spot partly because of massive infrastructure construction such as building a subway and other projects designed to better use rainwater. Harbin's heavy traffic during rush hour is more due to poor urban planning, according to the report.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
The EU is making clear it wants to use the void in US leadership on trade to nail down new trade agreements. The negotiations with the Mercosur trade bloc in Latin America have been going on in fits and starts for more than a decade. But the EU and key Mercosur members like Argentina are now pushing to conclude a deal by the end of this year. That would be a big statement planted right in the US’s backyard.
Yu Xiuhua, born with cerebral palsy, lived a quiet village life. She is now a literary sensation whose vivid, erotic poems are “stained with blood.”
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Anti-dumping cases were much easier to bring in the US than in the EU where companies first had to pass a public interest test.
Companies are always looking to save money, and outsourcing some roles to freelancers can help. Virtual assistants can perform many of the duties of full-time staffers, but with less commitment. These workers could help expand a business, or just encourage things to run more smoothly.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
201202/172834.shtmlChinese entrepreneur Wang Xing stays in touch with a sister in California and an uncle in Australia through chat software that offers a glimpse of how China's Internet companies can compete globally.
During last year's LFW, there were 250 anti-fur protesters, The Guardian reported, and a show in February saw an activist storm the stage at a Mary Katrantzou show.
Length-scale dependence of protein hydration-shell density
The sharp decline in unemployment will start to seem real
"We hope the mother will come to us and verify the facts. If it's true that the user is a 13-year-old who spent the money without consent, we can negotiate a refund," the Tencent employee said.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Bedrooms are up a curving staircase. A loft-like library overlooks the central atrium. Walls of glass in the master suite and its en-suite bathroom take in acres of marshland. The suite opens to a sun deck on the water side of the house. Both other bedrooms also have en-suite bathrooms. The lower level is finished as a gym, with a half bath and a garage with space for several cars.
About this collection
7. Make sure you don’t ask silly questions such as; is this Chelsea versus England?